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API (ISAPI) filter

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Hi,

We have an TMG 2010 that is running on a server 2008 R2 that also is our Exchange edge and also has FPE 2010. we access our OWA that is behind this TMG server, laatly I come accross this issue, when I access the owa link it gets open then when I try to loggin to the owa rendomly see this error in browser:

Error Code: 403 Forbidden. The server denied the specified Uniform Resource Locator (URL). Contact the server administrator. (12202)

streang thing is when I close and open the web browser then I can login to the OWA without any issue. we use this publish rule for more then 2 years and never has any issue.

I did also run the logs on the TMG server and at the same time I get the error in the browser get this error on the TMG server:

NTS53 11/1/2012 8:58:24 AM
Log type: Web Proxy (Reverse)
Status: 12210 An Internet Server API (ISAPI) filter has finished handling the request. Contact your system administrator.
Rule: OWA of company
Source: External (132.XX.XX.230:1068)
Destination: Local Host (10.0.10.11:443)
Request: GET http://mail.mycompany.nl/owa/ev.owa?UA=0&oeh=1&ns=PendingRequest&ev=PendingNotificationRequest&canary=b1eeb49f700b42c48172f0f65e756c69
Filter information: Req ID: 0f1b7dff; Compression: client=Yes, server=No, compress rate=0% decompress rate=0% ; FBA cookie: exists=yes, valid=yes, updated=no, logged off=no, client type=public, user activity=no
Protocol: https
User: domain.local\postmaster@domain.nl
Additional information
Client agent: Mozilla/4.0 (compatible; MSIE 8.0; Windows NT 5.2; Win64; x64; Trident/4.0; .NET CLR 2.0.50727; .NET CLR 3.0.4506.2152; .NET CLR 3.5.30729)
Object source: Internet (Source is the Internet. Object was added to the cache.)
Cache info: 0x4000000 (Response includes the WWW-AUTHENTICATE header.)
Processing time: 16 MIME type:

Any idea why is this happening?

Thanks


Shahin


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