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Sudden Skype Cant login via TMG 2010 Proxy server

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Anybody Help us out. We are using TMG 2010 Sp1 Proxy in our Office and skype was working Great. But suddenly from Today SKype is not login via Proxy server. We even tried with simple Allow all rule. And skype giving error of "Skype Can't Connect". We are sure Microsoft has done some changes on Skype. ON TMG we are Getting error message logs on user traffice

"Failed Connection Attempt" 

Status: 10061 NO connection Could be made because the Target machine actively refused it.

 

or Status 10060 A connection attempt failed because the connected party did not properly  respond after a period of time, or established connection failed because connected host has failed to respond.

 

Destination IPs are : 91.190.218.40:443, 91.190.216.17:443  137.116.193.65  90.136.190.167 etc


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